Grand Rounds Recap - 4/22/15

Grand Rounds Recap - 4/22/15

Oral Boards Practice Cases

Case 1 - 22 yo F in a "coma" with normal vital signs. Not responding to Narcan and Dextrose. Found in a garage. On exam, she has sluggish and dilated pupils. pH 6.98, pCO2 29, bicarb 2

High concern for toxic alcohol ingestion: consult DPIC and nephrology for dialysis

  • Fomepizole is the antidote for ethylene glycol only
  • Can use ethanol drip to treat both ethylene glycol and methanol
  • Replace folate aggressively and early 
  • Methanol is metabolized to formic acid, if you give folate you can prevent methanol from going down the formic acid pathway
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