TTP, ITP, HUS, DIC - the category of hematologic emergencies is rife both with three-letter acronyms and potentially devastating complications for those patients afflicted with them. Told from the perspective of an internist, this article by medicine chief resident Dr. Baez details a case of thrombotic thrombocytopenic purpura (TTP) through the entirety of the patient's care, beginning with its presentation in the ED and ending with patient's ultimate recovery. In this article, Dr. Baez also details the newly minted, clinically-validated PLASMIC score, a scoring system that can be used in the ED to facilitate diagnosis of TTP. Check it out!