Grand Rounds Recap 3.11.20


Airway Grand Rounds WITH Dr. Carleton

Some Definitions

  • A course of intubation is characterized by a strategy and/or a device choice.

    • For example: EGD, direct laryngoscope, video laryngoscope, endoscope, knife

    • The number of courses of reflects the soundness of the cognitive approach to the airway

  • An attempt at intubation is the active of trying to visualize the glottis or to pass a tube into the trachea.

    • Attempts occur within a course.

    • The number of attempts often reflects the technical skill with which the procedure is performed

  • Example:

    • Patient with multiple GSWs to the thorax. An iGel is placed to facilitate preoxygenation (1st course, 1 attempt). The iGel is removed and direct laryngoscopy is attempted three times with unsuccessful visualization using a Miller 4 blade (2nd course, 3 attempts). Direct laryngoscopy is reattempted with a Mac 4 blade, visualizing the glottis but unable to pass the ETT (3rd course, 1 attempt). The patient is eventually intubated by video laryngoscopy with a D-blade (4th course, 1 attempt).

Opportunities for QI

  • Appropriate depth

    • Female: 21cm to 23cm

    • Male: 23 to 25cm

  • If someone with an iGel is ventilating well, consider generous paralysis to prevent emesis and aspiration.

    • Additionally, consider intubating through an iGel blindly or endoscopically.

COVID19

  • Wang et al JAMA 2020

    • 138 hospitalized for COVID-19 in Wuhan, China

      • 29% were hospital personnel

    • 26% were admitted to the ICU

      • 31% developed ARDS

      • 42% were managed with NIPPV

      • 11% were managed with HFNC

      • 47% were managed with mechanical ventilation

      • Overall, there was 4.3% mortality

  • Transmission: droplet, but can then be transmitted via fomite when droplets settle on surfaces

    • There is a question of whether this virus can be transmitted by airborne transmission

    • Be diligent in using airborne + droplet + contact precautions, especially during procedures which generate aerosols

  • To minimize airborne and droplet spread:

    • Place a high-efficiency hydrophobic, viral/bacterial filter between the patient and the ventilation device (including resuscitation bags)

    • Have the exhaust filter appropriately placed on resuscitation bags

    • Place a mask on a patient with a nasal cannula, especially HFNC

    • Minimize BiPAP: standard BiPAP machine vents expired gases directly into the room without filtration

      • Use a ventilator to provide pressure support + PEEP with a non-invasive mask as a way to pre-oxygenation a patient prior to intubation

    • When intubating, strongly lean on RSI over fiberoptic intubations


R1 Clinical Knowledge: Face and Mouth INfections WITH Dr. Frankenfeld

  • Erysipelas

    • Much more demarcated borders compared to cellulitis, as this is secondary to infection of superficial skin structures

    • Can be treated with penicillin/amoxicillin

    • If bullous, more likely to be MRSA so would want to add additional antibiotic coverage

  • Impetigo

    • Classic honey-crusted lesions

    • Typically topical treatment is appropriate but can consider systemic treatment if there are “punched out lesions” or for more severe infections

  • Septic Cavernous Sinus Thrombosis

    • Anatomically, this is a sinus with a large number of structures coursing through, including the internal carotid artery and multiple cranial nerves

    • Presentation includes proptosis, opthalmoplegia, headache

    • With the valveless venous system throughout the cranium, it can easily spread throughout the rest of the venous drainage system intracranially

  • Parotitis

    • Viral is less likely to have intense erythema and swelling is more anterior to the mandible

      • Treatment is supportive care

    • Bacterial is more likely to have intense erythema with induration

      • You may be able to identify purulent drainage from Stenson’s duct

      • Will require treatment with antibiotics, such as Unasyn or clindamycin

  • Pharyngeal Infections

    • Viral pharyngitis can have an exudative pharyngitis, but more classically will include mucosal petechiae

    • Utilize appropriate testing strategies for bacterial pharyngitis, such as Centor Criteria

      • Also consider gonoccocal pharyngitis if the patient has high-risk sexual practices

      • Fusobacterium necrophorum

        • Can lead to Lemierre’s syndrome, which is a infectious thrombophlebitis of the internal jugular vein

        • Treat with penicillin and an additional agent with appropriate anaerobic coverage

        • The decision to use anticoagulation is heavily debated, but may be indicated for extensive disease or persistent bacteremia

    • Peritonsilar abscess

      • Hot potato voice, uvular deviation

      • Polymicrobial

      • Treatment includes antibiotics, drainage, and steroids

      • Drainage:

        • Needle aspiration is less painful that incision and drainage with a higher recurrence rate

        • Perform procedure on the superior pole of the tonsil

        • Avoid lateral structures, as this has increased risk of carotid puncture

    • Retropharyngeal abscess

      • Polymicrobial

      • Can extend into the mediastinum and cause mediastinitis

      • Utilize CT scan or lateral neck x-rays to look for thickening of the pre-vertebral space

  • Odontogenic Infections

    • Infections around the mandibular teeth typically spread to the deep neck structures

    • Infections around the maxillary molars typically spread into the maxillary space

    • Infections around the anterior teeth typically spread sublingually

    • Ludwig’s angina

      • Trismus, woody edema and edema of the floor of the mouth

      • This causes posterior displacement of the tongue and can lead to difficulties in airway management

      • Administer appropriate antibiotics, including MRSA in those at risk such as immunocompromised patients


R3 Taming the SRU: Loperamide Overdose WITH Dr. Li

  • Loperamide is highly protein bound and starts to have sodium blockage potential with 100-800mg per day

  • The misuse and abuse of loperamide has significantly increased over the last decade

    • This trend can also be mapped to the increased prevalence of opiate use disorder

  • Some patients who abuse loperamide will also take black pepper and grapefruit to potentiate the effects

  • Presents similar to opiate toxicity with altered mental status, miosis, and apnea or bradypnea

  • Slowed gut motility can lead to increased loperamide release over time

    • These patients may need additional naloxone dosing over time

  • Use sodium bicarbonate or hypertonic saline for sodium channel blockade

  • Other therapies include intralipid, plasma exchange, calcium, and ECMO


QI: HealthCare CHange Methodology WITH Dr. Thompson

  • Complicated process changes are unlikely to be adequately affected or successful when “fixed” by simple solutions.

  • PDSA Cycle

    • Plan: what will happen if we try something differently?

      • Define the objective

      • Plan for how to carry this change out

    • Do: let’s try it!

      • Carry out plan, focusing on one change at a time

      • Document problems

      • Begin data analysis

    • Study: did it work?

      • Complete data analysis and compare to predictions

    • Act: what’s next?

      • Is this change ready to implement?

      • Should you try something new?


Pediatric Simulation WITH Dr. Stratton

Pediatric Ultrasound

  • When performing a FAST exam, the first area where fluid will accumulate in pediatrics is in the pelvis.

  • When performing RLQ ultrasound to evaluate for appendicitis, begin your study with a linear probe where the iliac vessels overly the psoas muscle

    • Alternatively, ask the patient where they are having the most pain

Cases

  • Evan’s Syndrome: combination of ITP and autoimmune hemolytic anemia

    • Treatment includes steroids, IVIg

  • Osteomyelitis and Discitis

    • If patient is well appearing, considering awaiting bone biopsy before antibiotics

    • Be concerned about back pain in children