Grand Rounds Recap 8.07.2024
/ABEM updates - R4 Capstone - Sepsis Operations update - R3 taming the sru - traveler’s diarrhea
abem updates WITH dr. melissa platt, abem board of directors
Beginning 2026, ABEM will be requiring a new certifying exam to replace the previous oral boards. This was felt to be a necessary change in response to decreasing ITE scores and first-time board pass rates
The written exam will still be required and is not changing
The new certifying exam will be offered in-person in Raleigh, North Carolina with 9 sessions per year
There will be two case types: clinical care cases and objective structured clinical examination (OSCE) cases
Continuing certification requirements (aka CME) will be required every 5 years after passing the boards
ABEM will publish sample cases online in advance of the new certifying exam
r4 capstone WITH dr. lawton
A “frequent flier” in the ED is defined as someone with >4 ED visits per year
Occur more frequently in patients who are insured by Medicare and Medicaid
ED “super-utilizers” have >18 ED visits annually
Represent ~3% of all ED visits
For certain chief complaints such as abdominal pain, back pain, or headache, may account for up to 40% of all ED visits
High ED utilization is associated with adverse effects
Episodic, fragment care
At risk for both over- and under-treatment
Contributes to longer ED wait times and strain on the healthcare system
Contributes to ED physician burnout
The Emergency Department is often not best suited to meet these patients’ complex care needs
ED physicians are impacted by our biases, and it is important to recognize our explicit and implicit biases, especially when caring for ED frequent fliers and super-utilizers
sepsis operations update WITH dr. shewakramani
Sepsis is a condition that carries high morbidity and mortality
Bundled sepsis care has been shown to improve mortality
CMS definitions are important to recognize; especially because hospital reimbursement is affected by compliance with the sepsis bundle in an “all-or-nothing” fashion
Severe Sepsis
Source of infection PLUS
2 or more SIRS criteria:
Temp <36 or >38
HR >90
RR >20
WBC <4k or >12k or >10% bands
End Organ Dysfunction
Elevated creatinine, troponin, lactate, INR, or bilirubin
Decreased platelets
Septic Shock
Lactate >4
Hypotension
Sepsis Reassessment
Within 3 hours
Lactate measurement (repeat if >2)
Blood cultures
Antibiotics
IV Fluids (30 cc/kg bolus if in septic shock)
Within 6 hours (if septic shock)
Pressor initiation
Reassessment of tissue perfusion
CMS sepsis compliance data is available online to the general public
r3 taming the sru: “7 Airways in 7 Hours” WITH dr. artiga
Inhalational injuries can be characterized by their anatomic location
Supraglottic Inhalational Injury
Caused by direct thermal injury
Usually present within the first 24 hours
Infraglottic Inhalational Injury
Caused by mucosal sloughing from inhalation of noxious chemicals
Presentation can be delayed by up to 36 hours
There is some data that we over-triage to intubation for burn victims, as many of these patients get extubated quickly
Little data on which burn victims need to be intubated, but there is some consensus that any signs of upper airway compromise such as stridor, respiratory distress, accessory muscle use, or any edema or blistering of the oropharynx
Our typical indications for intubation still apply: failure to oxygenate, failure to ventilate, failure to protect airway, and anticipated clinical course
Pregnant patients are at high risk of physiologic compromise during the intubation period
Hormonal changes cause increased edema of the vocal cord structures
Diaphragm elevation reduces functional residual capacity
Pre-oxygenation is especially important
Consider an awake look intubation in ill patients who are less likely to tolerate the apnea period
Increased intra-abdominal pressures and reduced lower esophageal sphincter tone predisposes to vomiting
Positioning is very important in pregnant patients
Position the woman with the HOB at 30 degrees and left lateral tilt to improve venous return by reducing pressure on the IVC
diarrheal illnesses WITH dr. roche
Diarrheal illnesses carry significant morbidity and mortality worldwide
Food-borne illness tends to present within the first 6 hours after exposure, can be caused by the bacteria themselves or pre-formed bacterial endo-toxins
Traveler’s diarrhea can occur in >20% of travelers to high-risk regions (includes many areas of South America, Africa, and Southeast Asia)
‘Traveler’s diarrhea’ is a misnomer, can occur in patients that live in these regions
Most common cause is ETEC (enterotoxigenic E. coli)
Can have serious consequences in the young, elderly, and immunocompromised patients
Prevention:
Avoid drinking non-bottled or non-treated water or consuming ice or mayonnaise-based foods
Pepto-Bismol at high-doses (500 mg QID) can be effective in preventing traveler’s diarrhea
Rifaximin may be used for prophylaxis in high-risk individuals
Azithromycin is commonly prescribed for prophylaxis but is generally not recommended due to risk of resistance
Chronic GI illnesses and PPI use are associated with increased risk of traveler’s disease
Treatment
Single-dose ciprofloxacin
Previously first-line, though certain areas have high rates of resistance
Single-dose azithromycin (1000 mg once)
Life-Threatening Causes of Diarrhea
Cholera
Mortality rate approaches 50%, associated with significant hypovolemia and electrolyte derangements
Oral rehydration is the mainstay of treatment
Ideal “home regimen”: 6 tsps sugar + 1/2 tsp salt in 1L water
Doxycycline and azithromycin can be used for treatment to reduce length of illnesses, but many improve with rehydration alone
Typhoid
High risk of progressing to bowel perforation and death
Can be spread by fingers, flies, fomites, and feces (“Four F’s of Typhoid”)
EHEC (Enterohemorrhagic E. Coli)
Associated with hemolytic uremic syndrome (HUS), especially in children
Avoid treating children with bloody diarrhea with antibiotics, can increase the risk of developing HUS
Water Purification
Water in the United States is treated to reduce colony counts below pathogenic levels but not completely sterilized
Common commercial methods of treating water include flocculation, settling, filtration, purification, and disinfection (usually a halogen, such as chlorine, which stays in the water and can treat any downstream contamination; UV light can also be used)
If you have no way to treat your water, allowing it to sit and “settle” in a container for 2-3 days will cause most pathogens to sink to the bottom, allowing clean water to rise to the top
Allowing water to sit in bottles in the heat in regions near the equator can also be effective in disinfecting water